| Shirley Doane Senior Center | Senior citizen center | 1412 6th St E | Mon 9 AM–3 PM |
| Shoe Sensation | Shoe store | 2421 WI-25 Ste 6 | Mon–Tue 10 AM–8 PM |
| Shoe's Pub | Bar | 1321 N Broadway St | Daily 11 AM–2 AM |
| Signature A Aesthetics | Day spa | 512 Oak Ave | Fri 10 AM–8 PM |
| Silgan Containers Corporation | Manufacturer | 1416 Indianhead Dr E | Fri 7:30 AM–4 PM |
| Silver Dollar Bar & Restaurant | American restaurant | 315 Main St E | Mon–Thu 11 AM–2 AM |
| Smokedale Tobacco | Tobacco shop | 2521 Hils Ct | Daily 8 AM–10 PM |
| Southside Body & Bike | Auto body shop | N4413 469th St | Mon–Fri 8 AM–5 PM |
| Southside Property Management and Real Estate LLC | Property management company | 1621 Broadway St S | Fri 8:30 AM–4:30 PM |
| Speedway | Gas station | 1708 N Broadway St | Fri 5 AM–11 PM |
| St Joseph School | Private educational institution | 910 Wilson Ave | Mon–Thu 8 AM–4:30 PM |
| St Joseph's Catholic Church | Catholic church | 921 Wilson Ave | Mon–Fri 8 AM–4 PM |
| St. Paul's Lutheran Church and School WELS | Lutheran church | 1100 9th St E | Mon–Fri 7:30 AM–3:30 PM |
| Stainless Technologies | Manufacturer | 5408 3M Dr # B | Mon–Fri 8 AM–4 PM |
| Starbucks Coffee Company | Coffee shop | 1431 N Broadway St | Mon–Fri 4:30 AM–8:30 PM |
| Stark's Metal Works Inc | Steel fabricator | 815 Hofland Rd | Mon–Thu 7 AM–4:30 PM |
| Steadfast Handyman LLC | Handyman/Handywoman/Handyperson | E5644 690th Ave | Mon–Fri 8 AM–5 PM |
| Stelter Rentals | Student housing center | 533 Broadway St S | Mon–Fri 9 AM–5 PM |
| Stepping Stones of Dunn County | Food bank | 1602 Stout Rd | Mon–Fri 9 AM–4 PM |
| Stout Adventures | Recreation center | 220 13th Ave E | Fri 3 PM–8 PM |
| Stout Craft Co. Kitchen & Tap House | American restaurant | 1501 N Broadway St | Fri 11 AM–12 AM |
| Stout Student Association | Government office | 302 10th Ave E #118 | Fri 9 AM–5:15 PM |
| Street Level Ministries | Church | 1009 6th St E | Mon 6:30 PM–9 PM |
| Sunshine Learning Center | Preschool | 1921 Wilson St | Mon–Fri 7 AM–6 PM |
| Synergy Cooperative | Tire shop | 807 Main St E | Mon–Fri 8 AM–5 PM |
| Synergy Retirement Planning Strategies, L.L.C. - Jon Kroening | Financial planner | 393 Red Cedar St Ste 4 | Fri 11 AM–4:30 PM |
| T.L. Sinz Plumbing, Inc. | Plumber | E5609 708th Ave | Mon–Fri 7:30 AM–4:30 PM |
| Tainter Street Dental | Dentist | 1700 Tainter St # A | Fri 8 AM–1 PM |
| Tamayo Services, LLC | Lawn care service | Wilson St | Mon–Thu 8 AM–4 PM |
| Tanglewood Greens Golf & Restaurant and Event Center | Restaurant | 2200 Crestwood Dr | Mon–Thu 7 AM–9 PM |
| Ted's Pizza Palace | Pizza restaurant | 306 Main St E | Tue–Thu 11 AM–9 PM |
| TenX | Manufacturer | 1801 Indianhead Dr E | Mon–Fri 7 AM–5 PM |
| The Abbey Pub and Grub | Bar | 414 Main St E | Fri 12 PM–2:30 AM |
| The Barn at Copper Creek | Wedding venue | N 7681 500th St | Daily 8 AM–10 PM |
| The Blind Munchies Coffeehouse | Coffee shop | 621 Wilson Ave | Tue–Thu 9 AM–8 PM |
| The Bridge To Hope | Domestic abuse treatment center | 2110 4th Ave NE | Daily Open 24 hours |